Health Condition 1: F01-F99- Mental, Behavioral and Neurodevelopmental disorders
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age above 55 years. 2. Undergoing major surgery over 60 minutes 3. Can give informed consent themselves 4. Minimum cognitive performance required to participate is ACE-III score more than 88.
Exclusion criteria
Exclusion criteria: Patients with a history suggestive of dementia (either listed in the medical record or reported by the patient) or any neurological disorder. 2. History of alcohol abuse, chronic opioid or other substance abuse 3. History of cerebral surgeries, stroke. 4. History suggestive of psychiatric disease like schizophrenia, dementia, anxiety or other disorder affecting cognition, mental dysfunction 5. Prescription of central nervous systemâ??active medications (eg:antidepressants, antipsychotics, sedatives)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| presence of post-operative deliriumTimepoint: 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To determine the association between pre-operative frailty in elderly patients undergoing surgery under general anaesthesia with post-operative cognitive dysfunction. 2) To determine the association between sarcopenia in elderly patients undergoing surgery under general anaesthesia with post-operative delirium. 3) To determine the association between sarcopenia in elderly patients undergoing surgery under general anaesthesia with post-operative cognitive dysfunction. 4) To determine the correlation between sarcopenia and post-operative morbidity and mortality. 5) To compare the discriminative ability of modified frailty index and ASA classification to predict morbidity and mortality.Timepoint: 72 HOURS POST SURGERY 30 DAYS POST SURGERY | — |
Countries
India
Contacts
Public ContactAnjaleekrishna K
all india institute of medical sciences
Outcome results
None listed