Health Condition 1: F102- Alcohol dependence
Conditions
Interventions
Intervention1: Active high definition transcranial direct current stimulation: The central active electrode will be placed over the left dorsolateral prefrontal cortex that is marked by 5 cm laterall
Sponsors
Central Institute of Psychiatry
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with mental and behavioural disorder due to use of alcohol dependence syndrome, currently using the substance (F10.24) as per international classification of diseases 10th (ICD-10) clinical description and diagnostic guidelines (WHO, 1993) 2.Male 3 Age between 18 and 50 yrs 4. Ready to give informed consent. 5.Clinical institute withdrawal assessment for alcohol revised (CIWA-ar) protocol score less than 10. 6. Patients on tab naltrexone 50mg/day as an anticraving agent.
Exclusion criteria
Exclusion criteria: 1. Not willing to give consent 2.Any other co-morbid substance abuse except nicotine and caffeine 3.Participants having any co-morbid psychiatric disorders. 4. Participants with hepatic derangements or impaired liver function test (LFT). 5. Participants having any contraindication for undergoing HD-tDCS and fMRS study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glutamate and GABATimepoint: Baseline (CIWA-Ar10) and after end of sessions | — |
Secondary
| Measure | Time frame |
|---|---|
| OCDUS, ACQ,Timepoint: Baseline (CIWA-Ar10) and after end of sessions | — |
Countries
India
Contacts
Public ContactDr Sanjay Kumar Munda
Central Institute of Psychiatry
Outcome results
None listed