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Biomarker in sepsis and septic shock

Potential role of mitochondrial uncoupling protein 2 as a biomarker in patients with sepsis and septic shock: An observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/08/036051
Enrollment
70
Registered
2021-08-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R652- Severe sepsis

Interventions

None listed

Sponsors

Roopa Sachidananda
Lead Sponsor
Madhuri S Kurdi
Collaborator
Shobha Medegar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: patients with sepsis or septic shock based on quick SOFA ( Sequential organ failure Assessment) score will be enrolled in the study as per the third international consensus definitions for sepsis and septic shock

Exclusion criteria

Exclusion criteria: pediatric patients Age less than 18 years Primary and secondary immunodeficiency syndrome Treatment with or corticosteroids or immunemodulators in previous 6 months Burns Pregnancy History of blood transfusion 6 months prior to admission malignancy

Design outcomes

Primary

MeasureTime frame
blood uncoupling protein 2 levels in patients with sepsis and septic shockTimepoint: 28 days—

Secondary

MeasureTime frame
comparison of uncopling protein 2 levels with procalcitoninTimepoint: 0 days to 28 days;mortality of patientTimepoint: 28 day—

Countries

India

Contacts

Public ContactRoopa Sachidananda

KIMS Hubli

roopasac@gmail.com9448658220

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026