Health Condition 1: H188- Other specified disorders of cornea
Conditions
Interventions
Intervention1: Collagenase: In the study group
patients receive topical application of collagenase (0.2mg/ml) soaked surgical sponge for 15 mins followed by direct
application of human amniotic
membr
Sponsors
Hyderabad Eye Research Foundation
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient should be 18 years and above of age. 2. Patient should be able and prepared to complete all required clincial tests and examinations. 3. Patient should be diagnosed with an acute ( 4. Patient should not have any other ocular abnormality in the injured eye. 5. Able to provide informed consent prior to any study related procedures.
Exclusion criteria
Exclusion criteria: 1. Unwillingness to participate in the study. 2. Inability to come for all follow-up visits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of cases showing complete restoration (epithelialization) of the ocular surface on clinical slit-lamp evaluation using fluorescein staining.Timepoint: 28 days | — |
Secondary
| Measure | Time frame |
|---|---|
| The proportion of patients showing 2-line improvement in BCVA from baseline will be computed along with 95% CIs.Timepoint: The secondary end points will be at 3-months, 6-months and 1-year follow up visit. | — |
Countries
India
Contacts
Public ContactDr Sayan Basu
LV Prasad Eye Institute
Outcome results
None listed