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Effect of low pressure pneumoperitoneum with deep neuromuscular block in patients undergoing laparoscopic cholecystectomy.

To study the outcomes of low pressure pneumoperitoneum with deep neuromuscular block versus standard pressure pneumoperitoneum in patients undergoing laparoscopic cholecystectomy for gallstone disease: A Randomized Control Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035975
Enrollment
224
Registered
2021-08-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Low pressure pneumoperitoneum
8 to 10mm Hg with Deep neuromuscular blockade.: Patients allocated to this group will undergo laparoscopic cholecystectomy with low pressure pneumoperitoneum of 8 to 10 mm Hg with deep neuromuscular b
â?¥ 12- 14 mm Hg with Moderate NMB: Patients allocated to this group will undergo laparoscopic cholecystectomy with standard pressure pneumoperitoneum of 12 to 14 mm Hg with routine moderate neuromusc

Sponsors

All India Institute of Medical Sciences New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients undergoing laparoscopic cholecystectomy. 2. BMI 3. 18 to 65 years of age both male and female. 4. Patient is able to follow instructions. 5. Able to provide informed written consent.

Exclusion criteria

Exclusion criteria: 1. Age > 65 or 2. BMI > 35 3. Unable to give consent or patient refusal. 4. Unfit for general anaesthesia. 5. Pregnancy.

Design outcomes

Primary

MeasureTime frame
1. Ease of operation according to predefined surgical rating scale. 2. Time taken for completion of procedure Timepoint: At completion of surgery.—

Secondary

MeasureTime frame
1. Pain score at 1hr, 6 hr, 24 hr and 7 days after operation. 2. Conversion rates from low to standard pressure and to open. 3. Complications and other predefined parameters. Timepoint: At completion of surgery, 1 hour , 6 hour , 24 hour and 7 days.—

Countries

India

Contacts

Public ContactProf Dr Sunil Chumber

All India Institute of Medical Sciences, New Delhi

sunil_chumber@hotmail.com9871060404

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026