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To study the importance of oral hygiene and maintenance of oral hygiene in gum disease patients

EVALUATION OF ALKALINE PHOSPHATASE LEVELS IN SALIVA AND SERUM OF CHRONIC PERIODONTITIS PATIENTS: A CLINICO-BIOCHEMICAL STUDY

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035891
Enrollment
70
Registered
2021-08-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Patients who are found to have chronic periodontitis: Salivary, Blood and GCF samples of subjects who are found to have chronic periodontitis are collected and evaluated for alkaline ph

Sponsors

Preeti Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with at least 25 years of age (25-55 years) Subjects who have given written consent Subjects who will be available for follow-up • For Control Group: Participants with at least 20 natural teeth and probing pocket depth of 2-3 mm with no attachment loss and bleeding on probing with For Study Group: Participants had to have 5 qualifying sites in 2 quadrants with a minimum of 2 affected teeth in each quadrant with each site having probing depth >= 5 mm, CAL >= 3 mm, bleeding on probing.

Exclusion criteria

Exclusion criteria: Any history of metabolic or systemic disease History of irradiation in the head or neck area Smokers Pregnant or lactating women Has not undergone any periodontal therapy for past 1 year Patients who are not maintaining their oral hygiene and patients lacking motivation during phase 1 therapy

Design outcomes

Primary

MeasureTime frame
Salivary ALP level Serum ALP level GCF ALP level Timepoint: At baseline and 1 month after therapy

Secondary

MeasureTime frame
Gingival Index (Loe & Silness) Plaque Index (Silness & Loe) Probing pocket depth (PPD) Clinical Attachment Level (CAL) are recorded for studyTimepoint: At baseline and 1 month after therapy

Countries

India

Contacts

Public ContactPreeti Singh

Institute of Medical Sciences

preetisingh2907@gmail.com8528855513

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026