Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group A ââ?¬â?? 134 patients , 1 microgram/kg dexmedetomidine mixed in saline to make 5ml.: Dexmedetomidine at a dose of 1 Ã?¼g/kg (mixed with saline to a total volume of 5 ml) nebuli
Sponsors
no sponsor it is a academic trial
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients consent. 2) patients who were American Society of Anesthesiologists (ASA) physical status I and II . 3) age between 18 year and 60 years. 4) with normal airway belonging to both the genders undergoing elective surgery under general anaesthesia with endotracheal intubation.
Exclusion criteria
Exclusion criteria: 1) Patients who were not consenting for the study 2) predicted airway difficulty 3) pregnancy 4) renal failure,uncontrolled hypertension, seizure disorders, patient on anti-depressants/anti-psychotics,patients with a poor cardiopulmonary reserve and with body mass index (BMI) >30 kg/m2 were excluded from the study. 5) Patients on beta blockers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the role of nebulised dexmedetomidine dose 1 .5 microgram/kg compared with 1 microgram/kg given pre operatively for attenuation of hemodynamic response to laryngoscopy and intubationTimepoint: baseline, after nebulisation, post induction ,post-intubation at 1min, 5min and 10 min | — |
Secondary
| Measure | Time frame |
|---|---|
| to study the dose sparing effect on propofol used during induction.Timepoint: 1 min after intubation | — |
Countries
India
Contacts
Public ContactDr Priyanka Shrivastava
Rajendra Institute of Medical Sciences
Outcome results
None listed