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To find out, if heating and moistening of air, with a simple filter is as good as machine heating, during artificial breathing support in children.

Effect of Heat and moisture exchanger (HME) vs. heated humidifier (HH) on ventilator related adverse events in children â?? A pilot randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035878
Enrollment
60
Registered
2021-08-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J988- Other specified respiratory disorders

Interventions

Intervention1: Heat moisture exchanger: This is a passive method of humidification. This is cheap, user friendly associated with less risk for infection as compared with active method with some disadv

Sponsors

JIPMER Intramural Research Fund
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Children aged 2 - 15 years requiring invasive mechanical ventilation 2.Expected ventilation duration > 48 hours based on clinical judgement

Exclusion criteria

Exclusion criteria: 1.Children with SAM 2.Airway manipulation in last 90 days (me-chanical ventilation or surgery ) 3.Severe ARDS diagnosed at admission as per PALICC definition 4.Haemoptysis 5.Child being ventilated for primary airway pathology (Bronchial asthma, Bronchiolitis. Upper airway obstruction, Bacterial tracheitis, tracheobronchomalacia)

Design outcomes

Primary

MeasureTime frame
1.To compare the incidence of artificial airway occlusion requiring endotracheal tube change between two groups 2.To compare the incidence of Ventilator associated pneumonia (as per CDC definition) between two groups 3.To compare the incidence of Ventilator associated pneumonia â?? Physician diagnosed be-tween two groupsTimepoint: Ventilator related adverse event is measured as composite outcome with occurrence of either of the following events at the end of seven ventilator days

Secondary

MeasureTime frame
1.To compare the requirement of suctioning between two groups 2.To compare the duration of ventilation between two groups 3.To compare maximum Peak inspiratory pressure required during the study period be-tween two groups 4.To determine number of children in whom Heat moisture exchanger was discontinued 5.To compare survival at hospital discharge be-tween two groups Timepoint: Ventilator related adverse event is measured at the end of seven ventilator days

Countries

India

Contacts

Public ContactSivamurukan

Jawaharlal Institute of Postgraduate Medical Education and Research

narayanan.p@jipmer.edu.in9443458850

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026