Health Condition 1: J988- Other specified respiratory disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Children aged 2 - 15 years requiring invasive mechanical ventilation 2.Expected ventilation duration > 48 hours based on clinical judgement
Exclusion criteria
Exclusion criteria: 1.Children with SAM 2.Airway manipulation in last 90 days (me-chanical ventilation or surgery ) 3.Severe ARDS diagnosed at admission as per PALICC definition 4.Haemoptysis 5.Child being ventilated for primary airway pathology (Bronchial asthma, Bronchiolitis. Upper airway obstruction, Bacterial tracheitis, tracheobronchomalacia)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To compare the incidence of artificial airway occlusion requiring endotracheal tube change between two groups 2.To compare the incidence of Ventilator associated pneumonia (as per CDC definition) between two groups 3.To compare the incidence of Ventilator associated pneumonia â?? Physician diagnosed be-tween two groupsTimepoint: Ventilator related adverse event is measured as composite outcome with occurrence of either of the following events at the end of seven ventilator days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To compare the requirement of suctioning between two groups 2.To compare the duration of ventilation between two groups 3.To compare maximum Peak inspiratory pressure required during the study period be-tween two groups 4.To determine number of children in whom Heat moisture exchanger was discontinued 5.To compare survival at hospital discharge be-tween two groups Timepoint: Ventilator related adverse event is measured at the end of seven ventilator days | — |
Countries
India
Contacts
Jawaharlal Institute of Postgraduate Medical Education and Research