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A study to compare the conditions for intubation of two drugs used as muscle relaxants namely Cisatracurium and Rocuronium.

A Randomised Double-blind Study to Compare the Intubating Conditions of Cisatracurium and Rocuronium for Intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035869
Enrollment
216
Registered
2021-08-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Cistracurium: Cistracurium is a non depolarizing muscle relaxant that is used to achieve muscle relaxation for endotracheal intubation and surgical procedures. In this study, we would l

Sponsors

Malankara Orthodox Syrian Church Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing surgeries requiring general anesthesia (procedures requiring general anesthesia for one hour or more). ASA Status of I and II. BMI between 20 - 30 kg/m2.

Exclusion criteria

Exclusion criteria: Patients with anticipated difficult intubation. Chronic alcoholics. Patients with diseases affecting neuromuscular transmission. Patients on medications known to interfere with neuromuscular blockers.

Design outcomes

Primary

MeasureTime frame
Onset time and intubating conditions of Cisatracurium and Rocuronium based on TOF stimuli and Copper Grading system respectivelyTimepoint: Assessed at 30 seconds interval—

Secondary

MeasureTime frame
Hemodynamic parameters between the two drugs are compared. Duration of action of the two drugs in the given doses are compared.Timepoint: Baseline values of hemodynamic parameters noted, followed by at one minute interval before intubation and at every five minute interval after intubation up to 30 minutes.—

Countries

India

Contacts

Public ContactAnjali Anna Thomas

Malankara Orthodox Syrian Church Medical College and Hospital

rakheeksd79@gmail.com9495567033

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026