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Comparing two drugs given as drips in reducing blood pressure in patients undergoing keyhole surgeries

Comparison Of Intravenous Infusions Of Dexmedetomidine And Propofol On Attenuation Of Hemodynamic Changes During Laparoscopic Surgeries- A Prospective Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035856
Enrollment
60
Registered
2021-08-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous infusions of dexmedetomedine and propofol: dexmedetomidine infusion 0.5 µg/kg/h will be started after intubation in one group and propofol infusion of 100 µg/kg/min will b

Sponsors

RAJMOHAN S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA grade I or II scheduled for elective laparoscopic surgeries requiring general anesthesia. 2) Duration of surgery less than 90 minutes.

Exclusion criteria

Exclusion criteria: 1)Patients refusal 2)Pregnancy 3)Emergency surgeries 4)Patients with anticipated difficult airway 5)BMI >30 6)Patients with ischaemic heart disease, hypertension, diabetes mellitus. 7)H/o chronic respiratory, hepatic, renal diseases and on anti-psychiatric medications. 8)H/o drug allergy.

Design outcomes

Primary

MeasureTime frame
Reduction in blood pressure and heart rateTimepoint: From pre induction upto 90 minutes

Secondary

MeasureTime frame
Heart rate changes, . Recovery characteristics assesment based on modified Aldreteâ??s score and Ramsay Sedation Scale and side effectsTimepoint: Till 2 hours after extubation

Countries

India

Contacts

Public ContactDR S RAJMOHAN

Sri Lakshmi Narayana Institute of Medical Sciences

rajmd13@gmail.com9582827358

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026