Health Condition 1: G96- Other disorders of central nervoussystem
Conditions
Interventions
Intervention1: Intravenous dexmedetomidine: Group 1 will receive iv dexmedetomidine 0.5 micrograms per kg through infusion over 10 min before induction. They will also receive intranasal dexmedetomidi
Sponsors
King George Mrdical University
Eligibility
Inclusion criteria
Inclusion criteria: Patient belonging to ASA 1and 2 Patient belongings to age 18 to 70 years Patient giving informed and written consent
Exclusion criteria
Exclusion criteria: Patient with known allergy or hypersensitivity to dexmedetomidine Patient with history of ischemic heart disease, second or third degree heart block, head injury, uncontrolled hypertension, uncontrolled diabetes, pregnancy,and previous craniotomy incision Patient with respiratory disease and predicted difficult airway Patient who refuse to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare mean arterial pressureTimepoint: Baseline 5 min after, 10 min after after drug administration before laryngosopy and intubation, at 1 min, 3 min, 5 min after intubation,before pin insertion at 1min, 5 min, 10 min,20 min,30 min,60 min afterpin insertion,sedation status at baseline and 10 min after drug administration | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare systolic and diastolic blood pressure along with sedation score and adverse effectsTimepoint: Baseline 5 min after, 10 min after after drug administration before laryngosopy and intubation, at 1 min, 3 min, 5 min after intubation,before pin insertion at 1min, 5 min, 10 min,20 min,30 min,60 min afterpin insertion,sedation status at baseline and 10 min after drug administration | — |
Countries
India
Contacts
Public ContactGarima Singh
KGMU
Outcome results
None listed