Comparison of intrathecal bupivacaine plus dexmedetomidine vs intrathecal bupivacaine plus clonidine for prolongation of analgesia in lower limb orthopedic surgeries

"comparision of itrathecal dexmedetomidine and clonidine as an adjuvant to bupivacaine for lower limb surgeries : A A randomized double blind study"

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/08/035767

Enrollment

Registered

2021-08-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified Health Condition 2: V99- Unspecified transport accident

Interventions

Intervention1: Inj Dexmedetomidine 5 mcg with inj bupivacaine 15 mg: inj. dexmedetomidine 5 mcg will be given as an adjuvant to bupivacaine(15 mg) for prolongation of analgesia in sub arachnoid block

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status I & II 2.Scheduled for traumatic lower limb orthopedic surgeries under subarachnoid block

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Uncontrolled hypertension 3.Allergy to any drug 4.Cardiac,Respiratory and Neurological dysfunction 5.Sedative drugs consumption 6.Any contraindication for subarachnoid block 7.Height of block above T8 8.Tumor and vascular surgeries of lower limbs

Design outcomes

Primary

Measure	Time frame
Duration of analgesia Timepoint: Every 5 minute up to 30 minute and then every 15 minute till completion of surgery	—

Secondary

Measure	Time frame
1.VAS score 2.patient satisfaction 3.onset of sensory and motor block 4.duration of sensory and motor block 5.side effect and complicationTimepoint: Every 5 minute up to 30 minute and then every 15 minute till completion of surgery	—

Countries

India

Contacts

Public ContactDr Trilok Singh Netam

Pt. J.N.M.Medical college Raipur

kamalsahare62@gmail.com9425206894

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026