Compsrison of two medicines dexmedetomidine and midazolam given through nasal route in children undergoing heart related procedures, for sedation and easy separation from their parents.

Comparison of intranasal dexmedetomidine and midazolam for sedation and ease of separation from parents in children umdergoing cardiac procedures.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/08/035746

Enrollment

Registered

2021-08-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F419- Anxiety disorder, unspecified

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine (DEX) is a strong and fast-acting alpha-2 adrenergic receptor agonist that is used as a premedication in various circumstances due to its sedative and a

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 1 to 10 years, American Society of Anaesthesiologists (ASA) physical status II to III, of either sex.

Exclusion criteria

Exclusion criteria: 1. Those with known allergy to dexmedetomidine and midazolam. 2. Difficult airway. 3. Haemodynamically unstable children

Design outcomes

Primary

Measure	Time frame
Child Parent Separation Score of 1Timepoint: Child Parent Separation Score Assessment at 10 min	—

Secondary

Measure	Time frame
Ramsay Sedation Score of 2Timepoint: Assessment at 10 min	—

Countries

India

Contacts

Public ContactDR Pankaj arora

VMMC AND SAFDARJUNG HOSPITAL

pavannayar1957@gmail.com9971935269

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026