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What is better for pain relief in patients with chronic knee pain due to osteoarthritis knee? Ultrasound guided local anaesthetic injection or steroid

To assess the effectiveness of Ultrasound guided genicular nerve block using 0.5% Bupivacaine in comparison with Ultrasound guided intra articular injection of 40mg Depo-Medrol in the management of chronic osteoarthritis knee pain-Double blinded randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035737
Enrollment
50
Registered
2021-08-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Genicular nerve block using 0.5% bupivacaine: Ultrasound guided genicular nerve block using 0.5% bupivacaine 2ml each to superolateral, superomedial and inferomedial genicular nerves al

Sponsors

Christian Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Chronic osteoarthritis knee with more than 3 months of pain with pain scored by visual analog scale more than or equal to 40mm Radiological osteoarthritis grade greater than Kellegren Lawrence grade 2 Refractory knee osteoarthritis pain not alleviated with first line of treatment Well controlled diabetes No signs of active infection at injection site

Exclusion criteria

Exclusion criteria: Patients who underwent prior knee surgery or surgery scheduled in the next 3 months Patients with severe knee joint instability Patients with serious neurological or psychiatric illness Those received steroid or hyaluronic acid injection therapy in last 3 months Those who on anticoagulant medication use and those with severe bleeding diathesis Patients with hypersensitivity to local anaesthetics or steroids

Design outcomes

Primary

MeasureTime frame
Mean change in knee pain assessed by Visual Analog ScaleTimepoint: At 1,4 and 12 weeks

Secondary

MeasureTime frame
Mean change in Lequesne Functional Index Incidence of adverse events Compliance to home based programmeTimepoint: At 1, 4 and 12 weeks

Countries

India

Contacts

Public ContactKalaivani P

Christian Medical College, Vellore

judy@cmcvellore.ac.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026