Health Condition 1: V00-Y99- External causes of morbidity
Conditions
Interventions
Intervention1: Comparison of efficacy of Ondansetron and Palonosetron for prevention of post-spinal shivering in lower limb sugeries.: Patients of group A will be given Ondansetron 8mg before spinal a
Sponsors
Dayanand Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex ,aged 18-60 years belonging to ASA I â??III, after written informed consent.
Exclusion criteria
Exclusion criteria: 1. Failed spinal anaesthesia. 2. Prolonged surgical time leading to supplement/ conversion to general anaesthesia. 3. Any contraindication to spinal anaesthesia. 4. Patient needing blood transfusion. 5. Parkinsons disease. 6. Patient with known endocrine disease. 7. Diabetic autonomic neuropathy. 8. Patients having any dysarryrthmias on pre-operative ECG. 9. Known hypersensitivity to any of the drugs used in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of prophylactic Ondansetron and Palonosetron in reducing the incidence and severity of post spinal shivering.Timepoint: The hemodynamic parameters, core and peripheral body temperature will be monitored perioperatively and in PACU at 30 minutes interval. Sensory and motor blockade will be assessed. Any episode of shivering will be recorded, graded as per Wrench.Grade3,4 will be given rescue drug Tramadol 50mg IVbolus. | — |
Secondary
| Measure | Time frame |
|---|---|
| To observe hemodynamic changes and side effects ,if anyTimepoint: Hemodynamic parameters will be monitored perioperatively and in PACU for 6hours. | — |
Countries
India
Contacts
Public ContactDr Deepshikha
Dayanand Medical College and Hospital
Outcome results
None listed