FindTrial
Sign In

Comparison of inj. ropivacaine with dexmedetomidine and inj. levobupivacaine with dexmedetomidine in a regional anesthesia technique used to provide pain relief following urological surgeries

â??COMPARATIVE STUDY OF INTRATHECAL ISOBARIC ROPIVACAINE (0.5%) AND ISOBARIC LEVOBUPIVACAINE (0.5%) WITH DEXMEDETOMIDINE 0.1ml (10 μg) IN PATIENTS UNDERGOING UROLOGICAL SURGERIES UNDER SUBARACHNOID BLOCK: A PROSPECTIVE RANDOMIZED DOUBLE-BLIND STUDYâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035681
Enrollment
68
Registered
2021-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: N399- Disorder of urinary system, unspecified Health Condition 3: O- Medical and Surgical

Interventions

Intervention1: Subarachnoid block in patients undergoing Urological Surgeries: Intrathecal Isobaric Ropivacaine 0.5% (3.5ml/17.5mg) with Dexmedetomidine 0.1ml (10mcg) in patients undergoing Urological

Sponsors

Dr Bhagyesh Sushchendra Kame
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients Scheduled for Both Elective and Emergency Urological Surgeries under Spinal Anesthesia 2. American Society of Anaesthesiologist (ASA) grade I-II. 3. Age group between 18-65 years.

Exclusion criteria

Exclusion criteria: 1. Patient refusal / not willing for regional anaesthesia. 2. Patients using alpha 2â??adrenergic receptors antagonists, calcium channel blockers, angiotensinâ??converting enzyme inhibitors 3. History of allergy to study drugs 4. Post spinal surgeries, Spinal Deformities 5. Coagulopathy 6. Dysrhythmia 7. Major Hepatic, Renal and Cardiovascular Dysfunction 8. BMI >35 9. Height

Design outcomes

Primary

MeasureTime frame
To compare the onset and duration of Sensory and Motor blockade using Dexmedetomidine 0.1ml (10mcg) as adjuvant to 0.5% Isobaric Ropivacaine and 0.5% Isobaric Levobupivacaine in patients undergoing Urological Surgeries under Subarachnoid BlockTimepoint: to the point of complete resolution of the sensory block, when the patient requests analgesia for post-operative pain VAS more than 3 and till the time when the patient sums the ability to flex the knees Grade 0 using Modified Bromage scale within 24 hours post operatively—

Secondary

MeasureTime frame
To compare hemodynamics between these two groupsTimepoint: till patient complains pain vas score of more than 3 within 24 hours post operatively—

Countries

India

Contacts

Public ContactAnand Subramaniam

Chettinad Hospital and Research Institute

dranandmurugan@gmail.com9444486183

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026