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USE OF MULTIPLE PARAMETRERS FOR DIFFERENTIATING HIGH GRADE GLIOMA, PCNSL AND METASTASIS.

MULTI-PARAMETRIC APPROACH FOR DIFFERENTIATING HIGH GRADE GLIOMA, PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA AND METASTASIS BY USING PERFUSION AND DIFFUSION TECHNIQUES ON MRI.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/08/035674
Enrollment
245
Registered
2021-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C718- Malignant neoplasm of overlappingsites of brain

Interventions

Intervention1: Adc b 4000: Additional mri sequence to be taken along with adc b 0 and b1000

Sponsors

Tata Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i All cases to be scanned in house ii In cases of High grade glioma lesion should show restricted diffusion on either b1000 or on both b1000 and b 4000 iii Suspected cases of High grade glioma PCNSL and metastasis on initial scans which are later biopsy proven after MRI includes high index of suspicion on PET CT for PCNSL and biopsy proven or known primary cancer in cases of metastases iv No surgical or medical treatment prior to MRI scan

Exclusion criteria

Exclusion criteria: Low grade gliomas

Design outcomes

Primary

MeasureTime frame
To obtain and compare Cbv Psr and Adc b1000 and b4000 in ipsilateral disease vs contralateral non disease region in high grade glioma and metastasis and pcnslTimepoint: This is a longitudinal study with multiple time points—

Secondary

MeasureTime frame
To compare cbv and psr valuesTimepoint: Longitudinal study with multiple time points—

Countries

India

Contacts

Public ContactPallavi Aughad

Tata memorial hospital

pallavipaughad@gmail.com7769073429

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026