comparsion between two drugs for the treatment of facial pigmentation

A comparartive study of the efficacy of once daily 4 % hydroquinone and 2% kojic acid cream for the treatment of facial melasma: A Randomized control trail

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/08/035625

Enrollment

Registered

2021-08-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L811- Chloasma

Interventions

Intervention1: Hydroquinone: Cream, 4%, Local application, bedtime, for 4 month Control Intervention1: Kojic acid: Cream, 2%, Local application, bedtime, for 4 month

Eligibility

Inclusion criteria

Inclusion criteria: 1. Those who are willing for study 2. Moderate to severe melasma 3. Age (18-60) years. 4. Mentally stable, oriented and coherent patients.

Exclusion criteria

Exclusion criteria: 1. Pregnancy and Lactation 2. Melasma inducing drugs. 3. Patients on photosensitizing drugs or thyroid hormones. 4. Patients on Hormone replacement therapy

Design outcomes

Primary

Measure	Time frame
To reduce the Melasma Area and Severity Index (MASI) ScoreTimepoint: 4 month	—

Secondary

Measure	Time frame
To improve the quality of life of the patientsTimepoint: 6 months	—

Countries

India

Contacts

Public ContactPK RATHORE

ROHAILKHAND MEDICAL COLLEGE

drpraveenderma@gmail.com9412332063

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026