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Comparison of two doses of phenylephrine to prevent intra operative nausea and vomiting in pregnant patients posted for cesarean section

ââ?¬Å?A comparative evaluation of two doses of phenylephrine infusion to prevent IONV in patient undergoing elective LSCSââ?¬?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035605
Enrollment
195
Registered
2021-08-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Phenylephrine infusion to prevent IONV in patients undergoing elective LSCS: Inj. phenylephrine 25microgm/min and 50microgm/min infusion intravenously with placebo (NS) controlled Contr

Sponsors

Departement of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant female patients with singleton pregnancy, taken up for Caesarean Section under spinal anaesthesia for various indications like previous Caesarean Section, breech presentation, cephalopelvic disproportion, pregnancy following infertility treatment, cord around neck, non progression of labour.

Exclusion criteria

Exclusion criteria: 1. Patient refusal to participate in study 2. Emergency indication of Caesarean Section like antepartum haemorrhage, Placenta previa, abruptio placenta, fetal distress, obstructed labour, umbilical cord prolapse, preeclampsia, gestational diabetes, essential hypertension, more than two previous LSCS, history of PPH, multiple gestation. 3. Patients having contraindication for subarachnoid block. 4. Patient having associated systemic illness (hypo/hyperthyroidism, diabetic, neuromuscular disease ischaemic/ valvular/ congenital heart disease, psychiatric, hematological disorder, SLE). 5. History of seizures, coma, neurological signs or symptoms (Eclampsia) 6. Any allergy to local anaesthetic or any drug.

Design outcomes

Primary

MeasureTime frame
Total Incidence of IONVTimepoint: 45 min to 1 hr (intraoperative)

Secondary

MeasureTime frame
Total consumption of phenylephrineTimepoint: 45 min to 1 hr (intraoperative)

Countries

India

Contacts

Public ContactAnchal Jhawer

RNT Medical College, Udaipur

vbedimd@gmail.com9829025373

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026