Health Condition 1: E854- Organ-limited amyloidosis
Conditions
Interventions
Intervention1: menthol lotion: 1% menthol (1 gm/100ml) lotion, 0.5 ml of menthol lotion for every 1% body surface area, in two divided dose for 24 weeks or absence of pigmentation and itching, whichev
Sponsors
Pigmentary Disorder Society
Dr Kiran Preet Malhotra
Dr Parul Verma
Dr Suaib Luqman
Dr Usha Chandra
Eligibility
Inclusion criteria
Inclusion criteria: •Total duration of illness more than six weeks •Histopathologically confirmed cases of primary localized macular amyloidosis with congo red positivity •Affected body surface area (BSA)
Exclusion criteria
Exclusion criteria: •Pregnant/lactating females. •Patient those with known coexisting psychiatry and chronic ailments viz. diabetes mellitus, malignancy, HIV or HBV. •Lesion confined to face, axillae, and/or breasts. •Unwillingness to participate in study. •Known case of atopy, prior history of allergy to any topical medication. •History of intake of systemic or topical antihistamine, non steroidal anti inflammatory, steroid or other immunosuppressive drugs for the last 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 100% improvement in itching and pigmentation Timepoint: before or till 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| change in body surface areaTimepoint: at every 4 weeks upto 24 weeks;Change in degree of pigmentationTimepoint: every 4 weeks upto 24 weeks;Change in patternTimepoint: at every 4 weeks upto 24 weeks;change in site involvementTimepoint: at every 4 weeks upto 24 weeks;Histopathological changesTimepoint: before and after treatment completion;Improvement in itchingTimepoint: at every 4 weeks upto 24 weeks;Patient satisfactionTimepoint: at every 4 weeks upto 24 weeks | — |
Countries
India
Contacts
Public ContactDr Swastika Suvirya
King George Medical University, Lucknow
Outcome results
None listed