Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.30-60 years of age 2.Give informed consent. 3.Patient with moderate to severe periodontitis with probing pocket depth >= 5mm 4.>=20 teeth present 5.Systemically healthy patients
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women 2.Smokers 3.Undergone periodontal therapy in last 6 months 4.Received antimicrobial therapy(local and/or systemic) in last 6 months 5.Patients who were taking or had consumed anti-inflammatory agent in last 3 months. 6.Patients with any systemic disorder affecting periodontal health. 7. Regular users of mouthwash
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â?¢To assess and compare the clinical effects of subgingival application of HA gel and MTZ gel as an adjunct to root surface debridement(RSD) in the treatment of chronic periodontitisTimepoint: At baseline,6 weeks and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢To evaluate the expression of Hunam beta defensin-2 in GCF after subgingival application of HA and MTZ gels in patients with chronic periodontitis.Timepoint: At baseline and 12 weeks | — |
Countries
India
Contacts
KING GEORGES MEDICAL UNIVERSITY,LUCKNOW