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Effect of addition of steroids to local anesthesia on surgical extraction of impacted lower wisdom tooth.

A comparative evaluation of effect of addition of 8 mg Dexamethasone to 2% Lignocaine with adrenaline in impacted mandibular third molar surgery: A Split Mouth Randomized double blinded Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035560
Enrollment
70
Registered
2021-08-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K011- Impacted teeth

Interventions

Intervention1: dexamethasone: 2 ml of 2% Lignocaine with 1:200000 Adrenaline and 8mg Dexamethasone in 2ml distilled water Control Intervention1: distilled water: 2ml of 2% Lignocaine with 1:200000 Ad

Sponsors

Poorna P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects falling under ASA class 1 & 2. Subjects requiring surgical extraction of bilateral mandibular third molars in class II position B. Subjects with no acute inflammation, excessive caries, pain and pathology around the mandibular third molars Subjects who have signed the informed consent

Exclusion criteria

Exclusion criteria: Subjects with infection around third molars. Subjects with peptic ulcer. Subjects who are pregnant and lactating. Subject with diabetes mellitus, systemic endocrine disorders, hypertension, kidney diseases, blood clotting disorders, obesity. Subjects having an allergy to any of the drugs or materials to be used. Subjects who have used antibiotics in the past 2 weeks. Subjects who have used NSAIDs in the past 1 week. Subjects who could not cooperate Subjects who refused to take part in the study

Design outcomes

Primary

MeasureTime frame
the difference in time of onset and duration of local anesthesia. Timepoint: 1. baseline 2.2-8 hours after the procedure

Secondary

MeasureTime frame
the difference in pain, swelling, and mouth opening.Timepoint: 24 hours, 48 hours and 1 week

Countries

India

Contacts

Public ContactDrPoorna P

Manipal College of Dental Sciences, Mangalore

premalatha.shetty@manipal.edu

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026