Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: intravenous paracetamol ,Dexmedetomidine: 1 gram of paracetamol were infused over the period of 15 min immediately after induction. Dexmedetomidine infusion started 1mcg/kg over 10 min
Sponsors
Ashok G
Eligibility
Inclusion criteria
Inclusion criteria: I. Age 18 to 60 years, of both genders II. American society of Anesthesiologists Gradeâ??I, Gradeâ??II III. Patients posted for laparoscopic cholecystectomy procedures (duration being 1 to 2 hours).
Exclusion criteria
Exclusion criteria: 1) American society of anesthesiologists Grade- III, Gradeâ??IV, Grade V. (2) Anticipated difficult airway. (3) Mallampati Gradeâ??III and Mallampati Gradeâ??I V. (5) Patients who are on aminoglycosides, MgSO4, antidepressants, anticonvulsants and anti-arrhythmic (6) Known history of allergy to any of the study drugs. (7) Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Better analgesia intra-operatively and post -operatively, prolonged duration with minimal side effects. Total opioid requirement postoperatively and time to first rescue analgesia Timepoint: 1hrs,2hr,3hr,4 hr, upto 24 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate, Systolic blood pressure and Diastolic blood pressureTimepoint: 5 ,10 15,30,45min ,1hr,2hr,3 hr 4hrs, 5hr ,6hr interval | — |
Countries
India
Contacts
Public ContactSASWATH PATTNAIK
IMS SUM HOSPITAL AND MEDICAL COLLEGE
Outcome results
None listed