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Effect of varying(changing) the time interval between Fentanyl(opioid analgesic/pain relieving agent) and Etomidate (sedative/sleep inducing agent used for anaesthesia) administration on Etomidate requirement for induction(starting) of anaesthesia.

Effect of varying the time interval between Fentanyl and Etomidate administration on Etomidate requirement for induction of anaesthesia. - EVFERIA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035515
Enrollment
153
Registered
2021-08-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: randomized double blinded study: Effect of varying the time interval between Fentanyl and Etomidate administration on Etomidate requirement for induction of anaesthesia ,fentanyl dose 2

Sponsors

jubilee mission medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients who will give consent to take part in this study 2)Age group 18 to 60 years 3) American Society of Anesthesiologists (ASA) physicalstatus classI, II , III 4)Patients scheduled for elective surgery under GA

Exclusion criteria

Exclusion criteria: 1)Patient refusal for studyparticipation 2)ASA class IV and V 3)Allergic to etomidate and fentanyl 4)Presence of preexisting neurological orneuromuscular disorders 5)BMI >35 in females and >40 males (morbidly obese patients) 6)Patients with severe cardiovascular disease (NYHA 3, NYHA 4) 7)Psychiatric patients and patients onpsychotropic drugs 8) Parturient and breast-feeding mothers 9) Patients having adrenal pathology and septic patients (higher risk of adrenalsuppression

Design outcomes

Primary

MeasureTime frame
: To determine whether fentanyl would significantly reduce the dosage of etomidate required to abolish response to verbal commands or loss of response to noxious stimulusTimepoint: The response will be noted at the time end point of inductionwhich will take less than 10 minutes—

Secondary

MeasureTime frame
To determine the relation between dosage of etomidate and end point of sedation during etomidate anesthesia with fentanyl at varying time intervals. Timepoint: 18 months—

Countries

India

Contacts

Public ContactSelvin Thomas

Jubilee Mission Medical College , Thrissur

binilim@gmail.com9744850222

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026