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Analyzing the utility of blood coagulation test to diagnose blood clot lysis

Diagnosing and Categorizing Acquired Fibrinolysis using Global Hemostatic Assays.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/08/035510
Enrollment
476
Registered
2021-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D689- Coagulation defect, unspecified

Interventions

None listed

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All TEG request for Citrated Kaolin TEG test

Exclusion criteria

Exclusion criteria: Patients diagnosed with sepsis (ongoing project, so to avoid data duplication), age less than 18 years, Death within 48 hours, Patients who were discharged against medical advice, patients with a history of ongoing thrombolysis therapy, patients on anti fibrinolytic drugs and other modalities of TEG.

Design outcomes

Primary

MeasureTime frame
categorizing the diagnosed fibrinolytic activity into primary and secondary based on TEG algorithm. Sensitivity and Area under the curve for Thrombin generation assay in diagnosing fibrinolysis activity compared to thromboelastogram. Correlation between TEG and TGA paramters as per manufacturer algorithm.Timepoint: Primary outcome - 24 months

Secondary

MeasureTime frame
clinical correlation with the diagnosis of primary and secondary fibrinolysis. Correlation of laboratory tests and TEG parameters. Management given to the patient and clinical outcome of patientsTimepoint: 24 months

Countries

India

Contacts

Public ContactDr Ganesh Mohan

Kasturba Medical College Manipal

drganeshmohan@gmail.com9539788828

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026