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Comparing occurrence of dry eye following cataract surgery by phacoemulsification and MSICS

Comparison of clinical and inflammatory markers for dry eye disease following phacoemulsification and manual small incision cataract surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/08/035502
Enrollment
86
Registered
2021-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H259- Unspecified age-related cataract

Interventions

None listed

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with senile cataract above the age of 40 years undergoing cataract surgery by MSICS or phacoemulsification

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1.Patients developing intra-operative or post- operative complications. 2.Glaucoma patients undergoing cataract surgery on prior topical anti-glaucoma medications. 3.Patients using any topical medications on a long-term basis for other ocular conditions like glaucoma, uveitis, etc. 4.Patients with lid abnormalities (entropion, ectropion, trichiasis) or exposure changes due to thyroid eye disease or facial nerve palsy.

Design outcomes

Primary

MeasureTime frame
Among patients undergoing cataract surgery by manual small incision cataract surgery and phacoemulsification: i. To compare ocular symptom scores, Schirmerâ??s I values, TBUT values and corneal surface staining score pre-operatively and post-op day 1, 3 weeks and 2 months ii. To compare tear film inflammatory markers (IL-1β, IL-6) and meibomian gland changes pre-operatively and post-op day 1, 3 weeks and 2 months iii. To compare impression cytology score pre-op, 3 weeks and 2 months.Timepoint: pre-operatively and post-op day 1, 3 weeks and 2 months

Secondary

MeasureTime frame
To study the effect of age, gender and occupation on Schirmerâ??s I values, TBUT values, corneal surface staining score, impression cytology score, tear film inflammatory markers (IL-1β, IL-6) and meibomian gland changes in these patientsTimepoint: pre-operatively and post-op day 1, 3 weeks and 2 months

Countries

India

Contacts

Public ContactDr Geeta Behera

JIPMER, Puducherry

geeta.anandaraja@gmail.com04132296291

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026