Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group D: Drug Group - Oral Drug Tapentadol: Patient will be given one tablet of tapentadol 75mg orally with a sip of water 1hr prior to surgery.
Control Intervention1: Group C: Control
Sponsors
Department Of Anaesthesia and Intensive Care
Eligibility
Inclusion criteria
Inclusion criteria: American society of Anaesthesiologists (ASA) physical status I and II of either sex. BMI >= 20 to Duration of surgery 2-3 hours (i.e fracture shaft femur, fracture tibia, fracture ankle)
Exclusion criteria
Exclusion criteria: Pre-existing local infection at the site of spinal block. Patients with coagulopathy and bleeding disorders Contraindication or allergy to opioids. Patients having pain in any other area other than surgery site Patient having sensory or motor problem in the lower limb Patients who failed to understand VAS scoring system. Pregnant and lactating women Patients with current history of psychiatric illness, communication difficulties Patient on any psychotropic drugs, alpha 2 agonists or opioids medications within 28 days before scheduled surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preemptive role of drug Tapentadol on the duration of spinal anaesthesia(Sensory and motor blockade)Timepoint: Just after giving spinal anaesthesia sensory block checked by pin prick method and motor block by modified bromage score.Sensory and motor blockade will be assessed every minute for the first 10 minutes and thereafter every 10 mins during surgery and every 15 minutes, postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| onset of sensory and motor block, duration of motor block, time to first rescue analgesia, VAS score, Ramsay sedation score, cumulative opioid consumption during first 24 hours and any side effects. Timepoint: 4,8,12,24 hours post operatively | — |
Countries
India
Contacts
Public ContactDr Jasveer Singh
Government Medical College and Hospital ,Chandigarh
Outcome results
None listed