Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Administration of cisatracurium: Cisatracurium 0.1mg/kg IV for intubation and thereafter 0.02 mg/kg as needed for surgical relaxation.
Control Intervention1: Administration of atracuriu
Sponsors
Dr Arshad N N
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age : 3 to 12 years 2) ASA Patients: I andII 3) Gender : Male and Female 4) Surgery: Elective surgery under GA, expected duration > 30 minutes
Exclusion criteria
Exclusion criteria: 1) Parents not willing for consent 2) Patients having known allergy to muscle relaxants 3) Patients with airway problems suggestive of difficult intubation 4) More than two attempts of laryngoscopy 5) Patients with neuromuscular diseases like myasthenia and myopathies 6) Patients receiving medications that interfere with neuromuscular blockade like phenytoin, valproate,carbamazepine, ethosuximide,lamotrigine,leveteracetam 7) Patients with disorder of cardiovascular, respiratory hepatic or renal systems
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To compare the efficacy of atracurium and cisatracurium with respect to intubating conditions and hemodynamic stability.Timepoint: 180 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 To assess sideeffects of atracurium and cisatracuriumTimepoint: 180 minutes | — |
Countries
India
Contacts
Public ContactDr NK Agrawal
All India Institute of Medical Sciences
Outcome results
None listed