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TO STUDY ROLE OF EPITHELIAL MESENCHYMAL TRANSITION MARKER IN ORAL CANCER

THE ROLE OF EXPRESSION OF EPITHELIAL-MESENCHYMAL TRANSITION MARKERS IN ORAL CAVITY SQUAMOUS CELL CANCER: AN OBSERVATIONAL STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/08/035485
Enrollment
100
Registered
2021-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

None listed

Sponsors

AIIMS RISHIKESH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age â?? 18 to 70 years. 2.ECOG-PS 0-2. 3.Biopsy proved Oral cavity squamous cell carcinoma. 4.Treated with upfront surgery with curative intent. 5.Details of one-year regular follow-up available.

Exclusion criteria

Exclusion criteria: 1.Recurrent cancer. 2.Synchronous / metachronous cancer. 3.Prior anticancer treatment (Surgery, chemotherapy, radiotherapy, immunotherapy). 4.Patient not willing to participate in the study. 5.Complete required information not available.

Design outcomes

Primary

MeasureTime frame
To estimate the Prevalence of expression of Epithelial Mesenchymal Transition markers E cadherin N cadherin Vimentin ZEB1 in oral cavity squamous cell cancersTimepoint: TWO YEARS JANUARY 01 2020 TO DECEMBER 31 2022—

Secondary

MeasureTime frame
1. To study the correlation of Epithelial-Mesenchymal Transition markers expression with the disease stage and histopathological factors. 2. To determine the role of Epithelial-Mesenchymal Transition markers expression in predicting 1-year locoregional control rates Timepoint: TWO YEARS JANUARY 01 2020 TO DECEMBER 31 2022—

Countries

India

Contacts

Public ContactDR PRATIK SOLANKI

AIIMS RISHIKESH

drksrajkumar@gmail.com9940155250

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026