To compare two drugs for day care in anal and perianal surgeries

Open label randomised study to compare etomidate and propof ol for general anaesthesia in ambulatory anal and perianal surgeries

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/08/035482

Enrollment

Registered

2021-08-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K918- Other intraoperative and postprocedural complications and disorders of digestive system Health Condition 2: K918- Other intraoperative and postprocedural complications and disorders of digestive system

Interventions

Intervention1: Etomidate 0.1mg/Kg I/V bolus dozes and 0.05mg/kg re infused every 4-5 minutes till the completion of surgery. : Comparison with propofol for general anaesthesia in ambulatory anal and p

Eligibility

Inclusion criteria

Inclusion criteria: This open label randomized study will be conducted at Punjab Institute of Medical Sciences often approval of Institutional Ethical committee and registration of clinical trial on 60 adult patients of age group (18-60yrs), ASA grade I & II posted for anal and perianal surgeries of 25-30 minutes duration. Exclusion criteria: -

Exclusion criteria

Exclusion criteria: History of respiratory disease History of renal and liver disorder. History of haemodynamic instability History of allergy to propofol or etomidate

Design outcomes

Primary

Measure	Time frame
To compare clinical variables (hemodynamic stability, pain at the injection site, need for assisted ventilation during surgery, recovery time, postoperative pain score, and patientâ??s satisfaction between a etomidate (group-I) and propofol (group-II)Timepoint: 5 points	—

Secondary

Measure	Time frame
To compare incidence of intra-operative and post- operative side effects between two groups. Timepoint: Single;To compare incidence of intra-operative and post- operative side effects between two groups. To compare incidence of intra-operative and post- operative side effects between two groups. To compare incidence of intra-operative and post- operative side effects between two groups. Timepoint: Single	—

Measure

Time frame

To compare incidence of intra-operative and post- operative side effects between two groups. Timepoint: Single;To compare incidence of intra-operative and post- operative side effects between two groups. To compare incidence of intra-operative and post- operative side effects between two groups. To compare incidence of intra-operative and post- operative side effects between two groups. Timepoint: Single

—

Countries

India

Contacts

Public ContactBALWINDERJIT SINGH

Panjab institute of medical sciences Jalandhar

drbalwinder2000@yahoo.co.in9814087951

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026