Comparison of intravenous dexmedetomidine and low dose ketamine to prevent shivering in spinal anaesthesia

"To study efficacy of prophylactic intravenous dexmedetomidine and low-dose ketamine for prevention of shivering during spinal anaesthesia: a double blinded, randomized control trial"

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/08/035439

Enrollment

135

Registered

2021-08-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N401- Benign prostatic hyperplasia withlower urinary tract symptoms Health Condition 2: N210- Calculus in bladder Health Condition 3: N433- Hydrocele, unspecified Health Condition 4: N428- Other specified disorders of prostate Health Condition 5: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Prophylactic I.V dexmedetomidine: I.V infusion of Dexmedetomidine 0.3mcg/kg diluted in 10 ml normal saline over 10 minutes. Control Intervention1: Prophylactic I.V ketamine: I.V infusio

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA grade I & II Weight 40-80 kg Height >140 cm Posted for elective lower abdominal surgery under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Patients with ASA grade III & higher Temperature 38 degree celcius Allergy to study drugs BMI >35kg/sq meter Coagulopathies History of any cardiac and respiratory disease Psychiatric disease Failed spinal block

Design outcomes

Secondary

Measure	Time frame
Hemodynamic parameters Sedation score Drug related side effectsTimepoint: Up to 90 minutes/end of surgery	—

Primary

Measure	Time frame
Prevention/incidence of shiveringTimepoint: Prevention/incidence of shivering	—

Countries

India

Contacts

Public ContactDr sourabh jain

RNT medical college

Khemraj10@gmail.com9414759782

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026