Health Condition 1: C73- Malignant neoplasm of thyroid gland
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patient planned for total thyroidectomy with or without neck dissection. Patient giving consent to participate in study. Patient planned for completion thyroidectomy.
Exclusion criteria
Exclusion criteria: Patient who is not willing to participate in the study Patient is unfit for surgery under general anesthesia. Patient having inoperable primary disease of thyroid. Patient having secondary hypoparathyroidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the role of absolute iPTH decline and absolute serum ionised calcium decline at 1 hour and 1 day post thyroidectomy in predicting hypocalcemia. To evaluate the role of serum magnesium levels in post-thyroidectomy hypocalcemia Timepoint: To evaluate the role of absolute iPTH decline and absolute serum ionised calcium decline at 1 hour and 1 day post thyroidectomy in predicting hypocalcemia. To evaluate the role of serum magnesium levels in post-thyroidectomy hypocalcemia | — |
Secondary
| Measure | Time frame |
|---|---|
| To develop a composite scoring system for predicting patients at high risk for developing significant hypocalcemia in post-operative period To develop a protocol for initiating calcium and vitamin D supplementation based on biochemical results. To correlate Bethesda scoring system for thyroid cytopathology and TI-RADS system for thyroid lesion with histopathology Timepoint: At post operative day 0 and 1 | — |
Countries
India
Contacts
All India Institute of Medical Sciences