Health Condition 1: D693- Immune thrombocytopenic purpura Health Condition 2: D693- Immune thrombocytopenic purpura
Conditions
Interventions
Intervention1: methylprednisolone: intravenous methylprednisolone [15mg/kg (maximum 1g) infusion over 2-3 hours for three days] followed by oral prednisolone (1 mg/kg/day daily) up to six weeks
Contro
Sponsors
Kundan Mishra
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with diagnosis of ITP as per IMWG criteria 2. Patients of ITP who require corticosteroid therapy
Exclusion criteria
Exclusion criteria: 1. Patients age 2. Patients who denied to give consent. 3. Patients of secondary ITP. 4. Patients not willing to receive any therapy 5. Patients of ITP who requires observation or any other drug except corticosteroid and immunoglobulin 6. Patients who are allergic to corticosteroids 7. Patients who can not be followed up for at least two-month after beginning of the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| To estimate and compare adverse events associated with methylprednisolone in ITPTimepoint: six week;To estimate and compare the response rate (CR, OR) of methylprednisolone in ITPTimepoint: six-week | — |
Primary
| Measure | Time frame |
|---|---|
| To estimate and compare the changes in the platelet count after methylprednisoloneTimepoint: One-week, two-week, four-week, six-week | — |
Countries
India
Contacts
Public ContactKundan Mishra
Army Hospital (Research and Referral)
Outcome results
None listed