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To check for the effect if intravenous ondansetron in prevention of spinal induced fall in blood pressure and shivering

Evaluating the effect of intravenous ondansetron in prevention of spinal anaesthesia induced hypotension and shivering

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035388
Enrollment
50
Registered
2021-08-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Ondansetron: 5-HT3 receptor antagonist being widely used as an antiemetic agent, has been safely used to blunt the Bezoldâ??Jarisch reflex, resulting in less bradycardia an

Sponsors

sharda hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade 1 & 2 2. Age 18-60 years 3. Patients scheduled for surgeries under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patients in whom spinal anesthesia is contraindicated(absolute and relative contraindications) 2. Patients having known allergy to ondansetron, 3. Patients having hypertension (HTN) and coronary artery disease 4. Patients who are taking selective serotonin reuptake inhibitors or treatment for migraine

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of intravenous ondansetron in preventing spinal anaesthesia induced hypotension and shiveringTimepoint: 30 minutes—

Secondary

MeasureTime frame
a) To check for bradycardia b) To check for intraoperative nausea and vomiting. Timepoint: 2 hours—

Countries

India

Contacts

Public ContactDr Nupur Aggarwal

school of medical sciences and research

doc.shivi45@gmail.com9999096812

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026