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To assess the efficacy of methotrexate in extending the life of arterio-venous fistulas and artificial grafts in patients undergoing dialysis

To Assess The Efficacy of Ultrasound Guided Peri-stenotic Injectable Methotrexate In Preventing The Re-stenosis Of The Upper Limb Arterio Venous Fistula or Arterio Venous Grafts in chronic kidney disease patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035382
Enrollment
15
Registered
2021-08-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Methotrexate injection: After angioplasty / surgery for stenosis in Arterio venous fistula or artrerio venous graft patients will be injected (USG guided) with methotrexate peri- adven

Sponsors

Dr Ajay Kumar Dabas
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients presenting with upper limb Areterio venous fistula / Arterioveous graft stenosis and undergoing angioplasty or surgery for correction of stenosis will be included in this study

Exclusion criteria

Exclusion criteria: Patients unwilling or having allergy to methotrexate will be excluded from the study. Patients with underlying myelo-suppression or deranged Liver function would be excluded Patients not having adequate result following angioplasty or surgery will also be excluded.

Design outcomes

Primary

MeasureTime frame
Patency , diameter , flow rates would be assessed at presentation , at interval of 2 weeks till 6 months and if possible at eight months and twelve monthsTimepoint: At presentation and then at two weeks interval till 6 months and if possible at eight months and 12 months

Secondary

MeasureTime frame
Any adverse events noted because of Methotrexate injection would be notedTimepoint: during the course of study upto 4 months

Countries

India

Contacts

Public ContactAjay Kumar Dabas

Armed Forces Medical Services

ajay13dabas@gmail.com8130830066

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026