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comparing the analgesic effect between a local anaesthetic and a drug used for induction in alleviating the pain caused while administering a lipid emulsion drug during induction of general anaesthesia.

Comparison between effect of intravenous lignocaine and ketamine in alleviating propofol injection pain in patients undergoing surgeries under general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/08/035362
Enrollment
50
Registered
2021-08-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Alleviating propofol injection pain: Administering 15 mg ketamine or 21.3 mg lignocaine intravenously 30 seconds before propofol injection to reduce propofol injection pain during induc

Sponsors

J Sivagurunathan
Lead Sponsor
Chettinad Academy of Research and Education
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA PS 1 and 2 patients undergoing surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: Patient refusal study Known allergy for study drug Pregnant females Cardiovascular diseases, renal and hepatic dysfunctions ASA PS 3 and 4

Design outcomes

Primary

MeasureTime frame
To reduce the incidence of propofol injection pain in patients undergoing surgery under general anaesthesiaTimepoint: 30 seconds after giving study drug—

Secondary

MeasureTime frame
To reduce the severity of propofol injection pain in patients undergoing surgery under general anaesthesiaTimepoint: 30 seconds after giving study drug—

Countries

India

Contacts

Public ContactAshok Kulasekhar

Chettinad Hospital and Research Institute kancheepuram

ashokk_dr@yahoo.com9840498420

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026