Health Condition 1: F90- Attention-deficit hyperactivity disorders
Conditions
Interventions
Intervention1: Add-on Ayurveda intervention to Conventional treatment: 1) Tablet Ayushmana - 2 tablets twice a day.
2) Bramha Rasayana - 5 grams
twice a day.
3) Jyotishmati Taila - 5 drops twice a day
Sponsors
Central Council for Research in Ayurvedic Sciences
Eligibility
Inclusion criteria
Inclusion criteria: � Children and adolescents of both sex in age group of 6-15 years � Fulfilling DSM -5 criteria for the diagnosis of ADHD � Patients receiving treatment as per Standard of care. � Patients or parent/caregiver without any psychotic disease or any mental situation which may cause the concern to properly complete the questionnaires. � Patients whose can understand and fill up required forms.
Exclusion criteria
Exclusion criteria: 1. Known or suspected severe mental retardation or significant learning disorder & Children with co-existing moderate ââ?¬â?? severe Neuro-psychological conditions or autism spectrum disorder. 2. Subjects who require drug therapy or hospitalization for treatment of a chronic psychiatric illness. 3. Patient with inability to swallow the medication whole, and those with any unstable medical illness. 4. Parents who do not give consent for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Change in Conners Parent Rating Scale - Revised. 2) Change in Conners Teachers Rating Scale - Revised.Timepoint: 6 Months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in Gut MicrobiotaTimepoint: 6 months;Change in methylation pattern in epigenomeTimepoint: 6 months;Change in modified AIIMS-INCLEN Diagnostic tool for ADHD.Timepoint: 6 months;Change in neuropsychological functions 1) assessed on children (arousal of attention; reaction time; sustained attention; delay aversion; planning; and executive functions such as, working memory, cognitive inhibition, set/task shifting) 2) changes in parentââ?¬â?¢s report on the executive functions of their childrenTimepoint: 6 months;Change in T scores of Child Behaviour Check List (CBCL)Timepoint: 6 months;Changes in biomarkers of neurological implications BDNF, beta endorphins and Telomere shorteningTimepoint: 6 months;Changes in inter-relationships among the gut and neurological biomarkersTimepoint: 6 months;Changes in modulation of the functional brain network connectivity (during resting-state and stop-signal response inhibition task)Timepoint: 6 months;Safety of Ayurveda interventions assessed clinically and in biochemical parametersTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Kishore Kumar Ramakrishna
National Institute of Mental Health and Neurosciences
Outcome results
None listed