Health Condition 1: K819- Cholecystitis, unspecified
Conditions
Interventions
Intervention1: Group A will receive Inj. Clonidine: Pre-op vitals will be recorded. Patients will be given Inj. Clonidine (2mcg/kg bolus and 1mcg/kg/hr infusion after induction of Anaesthesia and Intu
Sponsors
Sawai Mansingh Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria: ASA I & II Age group 30-60yrs Patients of both sex Patients posted for elective laparoscopic Cholecystectomy Patients who have given informed written consent
Exclusion criteria
Exclusion criteria: Exclusion Criteria: Patients with systemic disorders like uncontrolled hypertension, Diabetes mellitus, severe cardiac, hepatic, respiratory, or renal disease. Patients with history of allergy to any of the used drugs in study. Patient with any psychiatric illness or having any history of opioid intake or alcohol intake Pregnant or breast feeding mothers. Patients on Calcium channel blockers, beta blockers, alpha 2 agonists, methyl dopa, tricyclic antidepressants, benzodiazepines, monoamine oxidase inhibitors Hypermagnesaemialective laparoscopic Cholecystectomy Pregnant or breast feeding mothers. Patients on Calcium channel blockers, beta blockers, alpha 2 agonists, methyl dopa, tricyclic antidepressants, benzodiazepines, monoamine oxidase inhibitors Hypermagnesaemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Heart Rate 1.Mean Systolic Blood Pressure 2.Mean Diastolic Blood Pressure 3.Mean MAPTimepoint: These parameters would be assessed - 1.Prior to induction(baseline) 2.At end of bolus infusion(T0) 3.5 min after pneumoperitoneum(T5) 4.10mins after pneumoperitoneum(T10) 5. 15mins after pneumoperitoneum(T15) 6. 20mins after pneumoperitoneum(T20) 7. 25mins after pneumoperitoneum(T25) 8. 30mins after pneumoperitoneum(T30) 9. 35mins after pneumoperitoneum(T35) 10. 40mins after pneumoperitoneum (T40) | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of- 1.Time to tracheal extubation, 2.Time to respond to verbal command(Awakening time), 3.Orientation time, 4.VAS Score, 5.Time to first rescue analgesia 6. No. of Rescue Analgesia in first 24hrs postoperative 7.Proportion of cases with side effectsTimepoint: VAS score will be assessed on following time periods: Immediately 30mins 1hr 3hr 6hr 12hr 24hr | — |
Countries
India
Contacts
Public ContactDr Simran Thareja
Sawai Mansingh Medical College, Jaipur
Outcome results
None listed