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To compare and evaluate the effectiveness of PRF with or without Osseograft in the treatment of intrabony defects in chronic periodontitis patients.

â??Comparative Clinical and Radiographic Evaluation of the Effectiveness of Bovine Derived Xenograft (OsseograftTM/DMBM) Alone and a Combination of Bovine Derived Xenograft and Autologous Advanced PRF (A-PRF+) in the Treatment of Intrabony Defects in Chronic Periodontitis Patients â??A Randomized Clinical Trial.â??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035236
Enrollment
40
Registered
2021-07-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Bovine Derived Xenograft: commercially available as Osseograft TM Intervention2: Bovine Derived Xenograft: Commercially available as Osseograft TM Control Intervention1: Bovine Derived

Sponsors

Lishana Farnomi Ch Momin
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient in the age group between 30-60 years. 2. Patient diagnosed with Chronic Periodontitis. 3. Patient who are non smokers and do not consume tobacco in any form. 4. Patients in good systemic health with no contraindications to periodontal surgery. 5. Patients having pocket depth greater than 5mm, intraosseous defects greater than 3mm with radiographic evidence of vertical or angular bone loss in the affected sites. 6. Involved teeth should be vital and asymptomatic.

Exclusion criteria

Exclusion criteria: 1.) One-walled osseous defects. 2) Patients suffering from any systemic diseases judge to impair normal healing and immune-compromised patients. 3) Patients who had received any type of periodontal therapy for the past 6 months. 4) Patients taking immunosuppressant drugs like corticosteroids. 5) Patients with a known history of allergy to Doxycycline or Chlorhexidine or any other medicine used in the study. 6) Patients taking any drug known to cause gingival enlargement. 7) Pregnant or lactating mothers. 8) Patients who were smokers or had tobacco in any other form. 9) Patients on anticoagulant therapy.

Design outcomes

Primary

MeasureTime frame
1. Plaque Index (P.I.) (Tureskey-Gilmore-Glickman Modification of Quigley Hein). 2. Gingival Index (G.I.) (Loe and Silness, 1963) 3. Probing Pocket Depth (PPD) 4. Clinical Attachment Level (CAL) Timepoint: At Baseline After 1 month After 3 month After 6 month—

Secondary

MeasureTime frame
The radiographic bone fill will be evaluated using Intraoral Periapical Radiographs of the surgical siteTimepoint: Baseline-at baseline. immediately after the surgery and 6 month post-surgery—

Countries

India

Contacts

Public ContactDr Praneeta Kamble

Nair Hospital Dental College,Mumbai,400008,Maharashtra, India

drpraneetakamble@gmail.com9820263468

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026