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Comparison of a blood product and a teeth protein to check for healing capacities

Comparative Evaluation of the Efficacy of A-PRF+ and Enamel Matrix Derivative (Emdogain®) on proliferation and migration of Periodontal ligament Fibroblasts â?? An invitro study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/07/035230
Enrollment
3
Registered
2021-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Dr Rupanjan Roy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Blood from healthy volunteers without platelet disorder for the preparation of A-PRF+. Teeth sample indicated for extraction due to orthodontic reasons or impacted third molars.

Exclusion criteria

Exclusion criteria: Teeth indicated for extraction due to periodontal reasons.

Design outcomes

Primary

MeasureTime frame
Comparison between A-PRF+ & Enamel Matrix Derivative (Emdogain) to evaluate cell proliferation and migration ratesTimepoint: 24, 48, 72 hours—

Secondary

MeasureTime frame
Analysis of the proliferation and migration rates using the combination of the reagents and with the individual reagentsTimepoint: 24, 48, 72 hours—

Countries

India

Contacts

Public ContactDr Rupanjan Roy

Manipal College of Dental Sciences, Manipal

pratibha.pk@manipal.edu9448724121

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026