Skip to content

A study to compare the effect of drugs,Levobupivacaine and Levobupivacaine with clonidine in erector spinae plane block for post operative pain management in patients undergoing open cholecystectomy.

Comparison between 0.25% Levobupivacaine and 0.25% Levobupivacaine with Clonidine in erector spinae plane block in patients undergoing open cholecystectomy: A prospective randomized double blinded study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035222
Enrollment
100
Registered
2021-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Erector spinae plane block in patients undergoing open cholecystectomy with levobupivacaine and levobupivacaine with clonidine as adjuvant.: 50 patients will receive 0.25% levobupivacai

Sponsors

Office of the Principal Midnapore Medical College And Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA physical status grade I grade II 2) Age group between 18-60 years of both sexs 3) Body Mass Index between 18.5 and 24 4) Patients scheduled for elective open cholecystectomy surgery

Exclusion criteria

Exclusion criteria: 1)Patients with severe cardio-respiratory disease 2)Patients with hepatic and renal disease 3)Patients with neurologic disorder 4)Patients with endocrine disorder 5)Patients with psychiartic problem 6)Thyroid disease 7)Diabetes mellitus 8)Pregnancy 9) Drug allergy to study drugs

Design outcomes

Primary

MeasureTime frame
To compare the effect of levobupavacaine only and levobupivacaine with clonidine in erector spinae plane block for post operative anaigesia in patients undergoing open cholesystectomy.Using clonidine as adjuvant may increase the period of postoperative analgesia.Timepoint: The quality of post operative analgesia will be assessed by using VAS at 15 min, 30 min and thereafter every 30 minutes till patient complains of VAS more than 4.Inj pentazocin 0.5 mg/kg will be administered intramuscularly when patients complains of VAS more than 4. If pain is not relieved 45 mins after pentazocin then 75 mg of diclofenac sodium will be administered intramuscularly as rescue analgesia.Total dose of analgesic drug will be calculated for first 24 hrs of after surgery.

Secondary

MeasureTime frame
to find out total amount of analgesic drugs used by patient in postoperative period in first 24 hrs.Timepoint: VAS score will be assessed at 15 mins, 30 mins and thereafter every 30 minutes till the VAS score becoms more than 4.then toatl amount of analgesics drugs will be calculated in first 24 hrs after completion of surgery.

Countries

India

Contacts

Public ContactAsim Kumar Maiti

Midnapore Medical College and Hospital

debasish77bhar@gmail.com8617753967

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026