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To compare the effect of pain relief between two drugs in patients undergoing surgeries on the upper limb

A randomised controlled trial to compare the anaesthetic potency and hemodynamic effects of levobupivacaine+buprenorphine and bupivacaine+buprenorphine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035211
Enrollment
80
Registered
2021-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S522- Fracture of shaft of ulna Health Condition 2: S518- Open wound of forearm

Interventions

Intervention1: Levobupivacaine with buprenorphine: Levobupivacaine (0.5%) 30 ml with buprenorphine (0.3mg) to anaesthetise upper limb with brachial plexus block using peripheral nerve stimulator for s

Sponsors

Karnataka institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18-60 yrs with ASA physical status Iâ??II who are scheduled for elective upper limb surgeries under brachial plexus block.

Exclusion criteria

Exclusion criteria: 1.Known hypersensitivity to amide local anesthetics 2. Morbid obesity (150% the ideal weight or >130 kg).

Design outcomes

Primary

MeasureTime frame
onset of sensory blockade with levobupivacaine faster than bupivacaineTimepoint: checked at baseline and then every 5 minutes for 30 minutes—

Secondary

MeasureTime frame
Better hemodynamic stability in levobupivacaine groupTimepoint: Blood pressure and pulse rate checked at base line and every 5 minutes for 2 hours—

Countries

India

Contacts

Public ContactDr Pushpavathi Ture

karnataka institute of medical sciences, Hubballi

pushpadrture@rediffmail.com9448251597

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026