Comparison of post operative pain relief in cesarean delivery with buprenorphine and morphine when used along with 0.25%bupivacaine in ultrasound guided transversus abdominis plane block.

Comparison of burprenorphine and morphine an adjuvant to 0.25% bupivacaine for post operative analgesia with ultrasound guided transversus abdominal plane block in cesarean delivery.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/07/035203

Enrollment

Registered

2021-07-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Buprenorphine, Bupivacaine : Buprenorphine 150mcg diluted to 15ml mixed with 0.5% bupivacaine 15ml, so the total mixture (30ml) containing 150mcg buprenorphine and 0.25% bupivacaine.15

Eligibility

Inclusion criteria

Inclusion criteria: Patient with ASA physical status-2 posted for cesarean delivery

Exclusion criteria

Exclusion criteria: 1. Chronic pain disorder 2. Known allergy or hypersensitivity to the study drug 3. Coagulopathy 4.local infection at block site 5.patient refusal for the procedure

Design outcomes

Primary

Measure	Time frame
Post operative pain assessment (VAS score), Heart rate, Respiratory rate, Blood pressure, Oxygen saturation.Timepoint: All these parameters are measured every 15mins for 1st hour,then every hourly upto 12hours,Then every 4th hourly upto 24hours.	—

Secondary

Measure	Time frame
24 hour analgesic consumption, nausea, vomiting, pruritis,Timepoint: Monitored for 24 hours	—

Countries

India

Contacts

Public ContactM MUGUNDA RAJ

Sri manakula vinayagar medical college and hospital

drkrishnaprabu@gmail.com9943770977

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026