Comparison of two different doses of drug for sedation in patients undergoing operation under spinal anaesthesia

Comparative Evaluation of Two Different Doses of Intravenous Dexmedetomidine Infusion for Sedating Patients Undergoing Lower Abdominal General Surgical Procedures under Spinal Anaesthesia

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/07/035201

Enrollment

Registered

2021-07-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M628- Other specified disorders of muscle

Interventions

Intervention1: Maintenance doses of intravenous dexmedetomidine Group A - 0.2 microgram/kg/hour Group B - 0.4 microgram/kg/hour: Doses of dexmedetomidine -Group A - 0.2 microgram/kg/hour Group B - 0

Eligibility

Inclusion criteria

Inclusion criteria: 1)American society of anaesthesiology (ASA) physical status 1 and 2 patients.

Exclusion criteria

Exclusion criteria: 1)Patients undergoing laparoscopic surgeries. 2)Patients who have arrhythmia , heart failure , liver failure , renal failure or bleeding tendencies. 3)Patients with heart blocks , on calcium channel blockers and betablockers. 4)Allergic to study drug and local anesthetic. 5)Those who are not willing to participate in the study.

Design outcomes

Primary

Measure	Time frame
To evaluate the effect of intravenous Dexmedetomidine infusion on sedation and duration of analgesia.Timepoint: For intraoperative period and for 24 hours postoperatively.	—

Secondary

Measure	Time frame
To evaluate hemodynamic changes and side effects of study drug if any.Timepoint: For intraoperative period and for 24 hours postoperatively	—

Countries

India

Contacts

Public ContactDr Amulya P

Sapthagiri institute of medical sciences and research center

amulyapreyakumar74@gmail.com7411074111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026