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comparison between two bone filling agents,one using patients blood and other without patients blood.

â??Comparative Clinical and Radiographic Evaluation of the Efficacy of Bovine Derived Xenograft and Calcium Sulfate Hemihydrate (OsseomoldTM) with Autologous Injectable Platelet Rich Fibrin (i-PRF) and Bovine Derived Xenograft and Calcium Sulfate Hemihydrate (OsseomoldTM) with Normal Saline used in the Treatment Of Intrabony Defects in Chronic Periodontitis Patients â??A Randomized Clinical Trialâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035196
Enrollment
40
Registered
2021-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Bovine derived Xenograft plus calcium sulfate hemihydrate with normal saline: commercially available as OsseomoldTM for 6 month in intrabony defect Control Intervention1: Osseomold with

Sponsors

Pradnya dattatraya kadam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients in the age group between 20-60 yrs. 2)patients diagnosed with Chronic Periodontitis. 3)Patients who are non smokers or do not consume tobacco in any other form. 4)Patients are in good systemic health with no contraindication to periodontal surgery. 5) Patients having pocket depths >5mm, intraosseous defects > 3mm and with radiographic evidence of vertical / angular bone loss in the affected sites. 6) Involved teeth to be vital and asymptomatic.

Exclusion criteria

Exclusion criteria: 1) One-walled osseous defects. 2) Patients suffering from any systemic diseases or with a compromised immune system. 3) Patients who had received any type of periodontal therapy for the past 6 months. 4) Patients taking immunosuppressant drugs like corticosteroids. 5) Patients with a known history of allergy to Doxycycline or Chlorhexidine or any other medicine used in the study. 6) Patients showing unacceptable oral hygiene compliance during / after Phase I periodontal therapy. 7) Patients taking any drug known to cause gingival enlargement. 8) Pregnant and/or lactating mothers. 9) Patients who were smokers or had tobacco in any other form. 10) Patients on anticoagulant therapy. 11) Patients with bleeding disorders.

Design outcomes

Primary

MeasureTime frame
Plaque index(P.I.)(SILNESS&LOE,1964) Gingival index(G.I.)(LOE&SILNESS,1963) Probing pocket depth(PPD) Clinical attachment Level(CAL) Timepoint: Baseline 1 month 3 months. 6 months.—

Secondary

MeasureTime frame
Radiograph Bone fill will be evaluated using Intraoral radiographs of the surgical siteTimepoint: Radiographs will be taken at baseline post surgery and 6 months post surgery.—

Countries

India

Contacts

Public ContactDr Mala Dixit Baburaj

Nair Hospital Dental College

maladixit25@gmail.com9223340938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026