Health Condition 1: F314- Bipolar disorder, current episodedepressed, severe, without psychotic features
Conditions
Interventions
Intervention1: cTBS: cTBS treatment will be delivered over rDLPFC for 3 sessions for 5 days a week spaced 30 minutes apart.A stimulation intensity of 80 % of the motor threshold (MT) of the right abd
Sponsors
SGRRIMHS
Eligibility
Inclusion criteria
Inclusion criteria: 1) Diagnosis of moderate to severe Bipolar disorder with current episode of Depression 2) Baseline HAM-D Score >18 3) Right Handed nor Mo tensive patient
Exclusion criteria
Exclusion criteria: 1) Neurological Disorder such as epilepsy,organic brain damage or any neurological procedure. 2) Pacemakers or other metal parts in the body 3) ECT in the past 6 months 4) Any comorbid Psychosis 5) History of non response to rTMS treatment 6) Alcohol or any other substance dependence except Nicotine and Caffine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare the change in Depressive symptoms in Bipolar Depression among active and placebo groupTimepoint: Screening ,Baseline ,7th Day post initiation of therapy, 21st Day post initiation of therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess and compare change in anxiety symptoms in bipolar depressionTimepoint: Baseline ,7th Day post initiation of therapy, 21st Day post initiation of therapy;To assess and compare change in quality of life in bipolar depressionTimepoint: Baseline ,7th Day post initiation of therapy, 21st Day post initiation of therapy;To assess and compare change in sexual dysfunction in bipolar depressionTimepoint: Baseline ,7th Day post initiation of therapy, 21st Day post initiation of therapy | — |
Countries
India
Contacts
Public ContactGunjan Malik
SGRRM&HS
Outcome results
None listed