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To assess and compare the post- operative analgesic effect of caudal epidural block with Ropivacaine versus mixture of Ropivacaine and Dexmedetomidine in patients undergoing lumbosacral spine surgery under general anaesthesia.

Comparison of analgesic effect of Ropivacaine versus Ropivacaine with Dexmedetomidine used for caudal epidural block in patients undergoing lumbosacral spine surgery under general anaesthesia; A randomized double blind interventional study at S.M.S Medical College, Jaipur during 2020-2021

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035177
Enrollment
60
Registered
2021-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injection Ropivacaine 0.2%: Caudal epidural block with Injection Ropivacaine 0.2% (Total volume 20ml) Control Intervention1: Injection Ropivacaine 0.2% mixed with Dexmedetomidine 1mcg/k

Sponsors

Department Of Anaesthesiology Sawai Man Singh Medical College And Attached Hospitals Jaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing lumbosacral spine surgeries under general anaesthesia. 2. Patients willing to give written and informed consent to participate in study. 3. Adult patients aged between 20 and 50 years. 4. Patient of either gender. 5. Patients belonging to ASA Grade I and Grade II.

Exclusion criteria

Exclusion criteria: 1. H/O allergic reactions to local anesthetics. 2. Patients on anticoagulant therapy and H/O coagulation disorders. 3. Local infection at the proposed site of puncture for caudal anaesthesia. 4. Patients with neurological and psychiatric disorders. 5. Patient with contraindication with caudal block like pilonidal sinus, congenital anomaly of spine or meninges. 6. Patient who had undergone previous back surgeries. 7. Patients with history of arrhythmias, heart block, hypotension, bradycardia or any cardiac illness.

Design outcomes

Primary

MeasureTime frame
1. To determine the difference in Visual analogue scale score between the two groups. 2. To determine the difference in mean time duration for the need of first rescue analgesia between the two groups. Timepoint: 24 hrs—

Secondary

MeasureTime frame
1. To determine the difference in peri-operative hemodynamic parameters (HR, SBP, DBP, MAP) from the baseline value between the two groups. 2. To determine the difference in consumption of total dose of fentanyl intraoperatively between the two groups. 3. To determine the difference in sedation score between the two groups. 4. To determine the difference in side effects, if any between the two groups.Timepoint: 24 hrs—

Countries

India

Contacts

Public ContactDr KIRANDEEP KAUR

Sawai Man Singh Medical College And Attached Hospitals

drmamtasharma@hotmail.com9829566077

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026