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Comparative evaluation of preoperative nebulization with two doses of budesonide for post operative sore throat following endotracheal intubation under general anaesthesia

Comparative evaluation of preoperative nebulization with two doses of budesonide for post operative sore throat following endotracheal intubation under general anaesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035159
Enrollment
105
Registered
2021-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: N859- Noninflammatory disorder of uterus, unspecified Health Condition 3: K353- Acute appendicitis with localizedperitonitis

Interventions

Intervention1: Budesonide: Preoperative Nebulisation with 250 micrograms of budesonide made to 5ml for 10 minutes, 10 minutes before induction Intervention2: Budesonide: Preoperative nebulisation with

Sponsors

Ankush Garg
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Belonging to American society of Anaesthesiologists (ASA) physical status I and II undergoing laparoscopic surgery under general anaesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: 1)Patients with difficult airway 2)Patients with a history of pre-operative sore throat, oral surgeries, asthma, diabetes, chronic obstructive pulmonary disease, head and neck surgeries. 3)Patient with known allergies to study drug and rescue drugs. 4)Patients consuming non-steroidal anti-inflammatory drugs within 24 hours prior to the surgery or on systemic or topical steroid therapy or having taken steroid drugs within five days prior to the surgery. 5)Duration of surgery > 1 hour and < 4 hours.

Design outcomes

Primary

MeasureTime frame
Incidence and severity of Postoperative sore throatTimepoint: 0, 6, 12, 24 hours after extubation

Secondary

MeasureTime frame
Incidence of cough and hoarseness of voiceTimepoint: 0, 6, 12, 24 hours after extubation

Countries

India

Contacts

Public ContactDr Shruti Jain

Vardhaman Mahavir Medical College and Safdarjung Hospital

shruti.anaesth@gmail.com9212308441

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026