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Effect of dexamethasone nebulization on attenuation of sore throat, hoarseness of voice and cough in general anaesthesia.

Effect of Preoperative dexamethasone nebulization for attenuation of postoperative sore throat, hoarseness of voice and cough in general anaesthesia: A randomized controlled double blinded study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/07/035146
Enrollment
100
Registered
2021-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulization with Dexamethasone and Normal Saline: Nebulization with dexamethasone 0.16mg/kg and normal saline total volume 5ml, in pediatric patients undergoing various surgeries under

Sponsors

JLN Medical College Ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 6-14 years of either sex Undergoing surgeries under general anaesthesia in supine position Duration of surgery up to 2 hours ASA physical status â?? I,II

Exclusion criteria

Exclusion criteria: Age 14 years ASA physical status III and above Mallampati grade > 2 Any psychiatric disorder or history of epilepsy Neurosurgical patients with raised intracranial pressure Patients with cardiac anomalies Patients sensitive or allergic to study drug History of pre-operative sore throat, oral surgeries, asthma, chronic obstructive pulmonary disease, head and neck surgeries. Recent non-steroidal drug medication Anticipated difficult intubation Patient and/or his/her legally acceptable representative not willing to provide their voluntary written informed consent for participation in the study

Design outcomes

Primary

MeasureTime frame
To assess the incidence and severity of- Postoperative sore throat (POST) Postoperative Hoarseness of voice Post-operative CoughTimepoint: 0hr,2hr,4hr,6hr,12hr,24hr

Secondary

MeasureTime frame
Haemodynamic parameters (HR, SBP, DBP, MAP & SpO2) Side effects, if anyTimepoint: 0hr,2hr,4hr,6hr,12hr,24hr

Countries

India

Contacts

Public ContactDr Kavita Jain

JLN Medical College, Ajmer

drkavitajain15@gmail.com9414006151

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026