Health Condition 1: H406- Glaucoma secondary to drugs Health Condition 2: H403- Glaucoma secondary to eye trauma Health Condition 3: H405- Glaucoma secondary to other eye disorders Health Condition 4: H400- Glaucoma suspect Health Condition 5: H401- Open-angle glaucoma Health Condition 6: H402- Primary angle-closure glaucoma
Conditions
Interventions
Control Intervention1: Nil: Nil
Sponsors
Remidio Innovative Solutions Pvt Ltd
Aravind Eye Hospital Pondicherry
Eligibility
Inclusion criteria
Inclusion criteria: 1. Glaucoma Group:Any case of glaucoma with typical glaucomatous disc changes, confirmed by clinical evaluation and visual field test (primary open angle glaucoma(POAG), normal tension glaucoma (NTG), primary angle closure glaucoma (PACG), secondary glaucomas) 2.Normal Controls (including Ocular hypertension (OHT) and primary angle closure suspects (PACS) status post laser peripheral iridotomy (LPI)) 3.Disc suspects 4.Reliable Visual field (false positive (FP), false negative (FN)
Exclusion criteria
Exclusion criteria: 1.Patient with acute or sudden vision loss 2.Patient deemed to have narrow angles on gonioscopy and cannot be dilated (primary angle closure) 3.Co-existing retinal pathologies precluding view of disc including Proliferative diabetic retinopathy 4.Significant media opacity precluding adequate view of the disc 5. Participant has a condition that, in the opinion of the investigator, would preclude participation in the study (e.g., uncontrolled intraocular pressure, active eye infection, 6.Participant is contraindicated for imaging by fundus imaging systems used in the study: a.Participant is hypersensitive to light b.Participant recently underwent photodynamic therapy (PDT) c.Participant is photosensitive or is consuming medication that causes photosensitivity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess the sensitivity and specificity of the Medios AI in detecting referable glaucoma when compared to reference standard of glaucoma diagnosis made by glaucoma specialist following a complete evaluation.Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Assess the positive predictive value, negative predictive value of Medios AI for detecting referable glaucoma. 2)Assess the sensitivity of the Medios AI in detecting certain glaucoma. 3)Assess the accuracy of the automated vertical cup to disc ratio (VCDR) algorithm to that of the specialist during a stereoscopic clinical exam. 4)Agreement between automated VCDR, clinical stereoscopic disc exam and spectral domain optical coherence tomography (SD-OCT) Timepoint: 2 months | — |
Countries
India
Contacts
Public ContactDr Swati Upadhyaya
Aravind Eye Hospital
Outcome results
None listed